Study confirms amyloid “clearance” as a causal therapeutic effect of donanemab

6. November 2025

Lu M, Kim MJ, Collins EC et al. Posttreatment Amyloid Levels and Clinical Outcomes Following Donanemab for Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ 2 Randomized Clinical Trial. JAMA Neurol. 2025 Oct 13.

https://jamanetwork.com/journals/jamaneurology/fullarticle/2839837

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